11.22.06 Chemical Manipulation of SAH-p53-8 Purpose: To optimize, through asymmetric dihydroxylation of its olefin cross-link, the solubility properties of a stapled peptide that targets the oncoprotein HDM2 in osteosarcoma cells –Laboratory Notebook Number III of Fed Bernal, Ph.D. I literally stumbled into the field of cancer chemical biology. Having been trained as a synthetic organic […]
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